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Image Search Results
Journal: Genome Biology
Article Title: RnBeads 2.0: comprehensive analysis of DNA methylation data
doi: 10.1186/s13059-019-1664-9
Figure Lengend Snippet: Analysis of a large DNA methylation dataset of blood samples profiled using Infinium 450k. a Scatterplot showing the correlation between epigenetic age predicted from DNA methylation and reported chronological age for 729 healthy donors (three individuals were excluded because no chronological age was reported). b Positioning of the samples in two-dimensional space for sex prediction. c Statistical association between principal components (columns) and sample annotations (rows). Significant associations with p values below 0.01 are marked by filled circles, while non-significant values are represented as empty circles. d Principal component analysis for 792 blood-based DNA methylation profiles, comprising 732 peripheral blood samples and 60 sorted blood cell populations, using the same principal components as in panel c . Immune cell content was estimated using the LUMP algorithm. e Scatterplot showing the negative correlation between chronological age and the estimated fraction of CD4 + T cells
Article Snippet: RnBeads now provides dedicated methods for cross-platform analysis, making it possible to combine RnBeads data objects across the different versions of the
Techniques: DNA Methylation Assay